#include <spikingneuron.h>

Inheritance diagram for MilesDai:

Collaboration diagram for MilesDai:

Public Member Functions
	MilesDai (void)

virtual string	name (void) const

virtual int	dimension (void) const

virtual void	variables (vector< string > &varnames) const

virtual void	units (vector< string > &u) const

virtual void	operator() (double t, double s, double x, double dxdt, int n)

virtual void	init (double *x) const

virtual void	conductances (vector< string > &conductancenames) const

virtual void	conductances (double *g) const

virtual string	conductanceUnit (void) const

virtual void	currents (vector< string > &currentnames) const

virtual void	currents (double *c) const

virtual string	currentUnit (void) const

virtual string	inputUnit (void) const

virtual void	add (void)

virtual void	notify (void)

Public Member Functions inherited from HodgkinHuxley
	HodgkinHuxley (void)

Public Member Functions inherited from SpikingNeuron
	SpikingNeuron (void)

virtual	~SpikingNeuron (void)

double	gain (void) const

double	offset (void) const

Public Member Functions inherited from ConfigClass
	ConfigClass (const string &ident, int group=0, int mode=0xffff, int selectmask=0)

	ConfigClass (const ConfigClass &C)

virtual	~ConfigClass (void)

const string &	configIdent (void) const

void	setConfigIdent (const string &ident)

int	configGroup (void) const

void	setConfigGroup (int group)

int	configMode (void) const

void	setConfigMode (int mode)

void	addConfigMode (int mode)

void	delConfigMode (int mode)

int	configSelectMask (void) const

void	setConfigSelectMask (int mask)

void	addConfig (void)

void	readConfig (void)

virtual void	readConfig (StrQueue &sq)

virtual void	saveConfig (ofstream &str)

virtual int	configSize (void) const

virtual void	config (void)

virtual void	preConfig (void)

Protected Attributes
double	ECa

double	GCa

double	GKAHP

double	GLD

double	GDS

double	GCaGates

double	GKAHPGates

double	ICa

double	IKAHP

double	IDS

double	ILD

double	ISD

double	CaA

double	CaTau

double	CD

Protected Attributes inherited from HodgkinHuxley
double	C

double	PT

double	ENa

double	EK

double	EL

double	GNa

double	GK

double	GL

double	GNaGates

double	GKGates

double	INa

double	IK

double	IL

Protected Attributes inherited from SpikingNeuron
double	Gain

double	Offset

Additional Inherited Members
Public Types inherited from ConfigClass
enum	Action

Static Public Member Functions inherited from ConfigClass
static void	setConfigureClasses (ConfigureClasses *cfg)

Static Public Attributes inherited from SpikingNeuron
static const int	ScalingFlag = 16

static const int	ModelFlag = 32

static const int	DescriptionFlag = 64

Detailed Description

[ModelLib] The Miles-Dai model for spinal motoneurones with slowly inactivating sodium current

Author: Jan Benda

The two-compartment model is from G. B. Miles and Y. Dai and R. M. Brownstone (2005): Mechanisms underlying the early phase of spike frequency adaptation in mouse spinal motoneurones. J. Physiol. 566, pp. 519-532. However, all potentials are shifted by -60mV, all conductances are in muS, and capacitances in nF.

Constructor & Destructor Documentation

Member Function Documentation

string name ( void ) const

virtual

Returns: the name of the model.

Reimplemented from HodgkinHuxley.

int dimension ( void ) const

virtual

Returns: the dimension of the system.

See Also: variables(), operator()()

Reimplemented from HodgkinHuxley.

void variables ( vector< string > & varnames ) const

virtual

Parameters

[out] varnames the names of each of the dimension() variables. Gating variables (ranging between 0 and 1) should be a single lower-case character, potentials and equivalent potentials a single upper-case character, and concentrations should be in brackets (e.g. [Ca]).

See Also: dimension(), units(), operator()()

Reimplemented from HodgkinHuxley.

References HodgkinHuxley::variables().

void units ( vector< string > & u ) const

virtual

Parameters

[out] u the units of the variables returned by variables().

See Also: dimension(), operator()()

Reimplemented from HodgkinHuxley.

References HodgkinHuxley::units().

void operator()	(	double	t,
		double	s,
		double *	x,
		double *	dxdt,
		int	n
	)

virtual

Computes the derivative dxdt at time t with stimulus s given the state x.

Reimplemented from HodgkinHuxley.

References HodgkinHuxley::C, MilesDai::CaA, MilesDai::CaTau, MilesDai::CD, MilesDai::ECa, HodgkinHuxley::EK, HodgkinHuxley::EL, HodgkinHuxley::ENa, relacs::exp(), MilesDai::GCa, MilesDai::GCaGates, MilesDai::GDS, HodgkinHuxley::GK, MilesDai::GKAHP, MilesDai::GKAHPGates, HodgkinHuxley::GKGates, HodgkinHuxley::GL, MilesDai::GLD, HodgkinHuxley::GNa, HodgkinHuxley::GNaGates, MilesDai::ICa, MilesDai::IDS, HodgkinHuxley::IK, MilesDai::IKAHP, HodgkinHuxley::IL, MilesDai::ILD, HodgkinHuxley::INa, and MilesDai::ISD.

void init ( double * x ) const

virtual

Initialize the state x with usefull inital conditions.

Reimplemented from HodgkinHuxley.

void conductances ( vector< string > & conductancenames ) const

virtual

Returns in conductancenames the names of the individual ionic conductances that conductances(double*) const would return.

Reimplemented from HodgkinHuxley.

void conductances ( double * g ) const

virtual

Returns in g the values of the individual ionic conductances. The number of conductances is defined by the size of conductancenames the function conductances(vector<string>&) const returns.

Reimplemented from HodgkinHuxley.

References MilesDai::GCaGates, MilesDai::GDS, MilesDai::GKAHPGates, HodgkinHuxley::GKGates, HodgkinHuxley::GL, MilesDai::GLD, and HodgkinHuxley::GNaGates.

string conductanceUnit ( void ) const

virtual

Returns the unit of the conductances returned by conductances(double*) const, i.e. muS

Reimplemented from SpikingNeuron.

Referenced by MilesDai::add().

void currents ( vector< string > & currentnames ) const

virtual

Returns in currentnames the names of the individual ionic currents that currents(double*) const would return.

Reimplemented from HodgkinHuxley.

void currents ( double * c ) const

virtual

Returns in c the values of the individual ionic currents. The number of currents is defined by the size of currentnames the function currents(vector<string>&) const returns.

Reimplemented from HodgkinHuxley.

References MilesDai::ICa, MilesDai::IDS, HodgkinHuxley::IK, MilesDai::IKAHP, HodgkinHuxley::IL, MilesDai::ILD, HodgkinHuxley::INa, and MilesDai::ISD.