Artificial synaptic conductance with current pulses to measure resistance.

Author

Jan Benda

Version

1.0 (Apr 05, 2014)

Periodically inject current pulses for monitoring the cell's resistance. At the same time an artificial synaptic conductance can be injected via dynamic clamp.

This RePro reproduces the dynamic clamp experiment of figure 1 in Andrew A. Sharp, Michael B. O’Neil, L. F. Abbott, and Eve Marder (1993): Dynamic Clamp: Computer-Generated Conductances in Real Neurons. J Neurophysiol (96), 992-995.

Options

• Current pulses
  • pulseamplitude=-1nA: Amplitude of current pulses (number)
  • pulseduration=100ms: Duration of current pulses (number)
  • pulseperiod=1000ms: Period of current pulses (number)
  • before=1000ms: Time before onset of synaptic current (number)
  • after=1000ms: Time after end of synaptic current (number)
  • pause=1000ms: Duration of pause between outputs (number)
  • repeats=10: Repetitions of stimulus (integer)
• Synaptic current
  • enableconductance=false: Inject synaptic current (boolean)
  • conductancetau=1000ms: Synaptic time-constant (number)
  • conductanceamplitude=1nS: Amplitude of synaptic conductance (number)
  • reversalpotential=0mV: Reversal potential of synaptic conductance (number)